EACH FILM COATED CONTAINS: AMITRIPTYLINE HYDROCHLORIDE I.P. EQV. TO AMITRIPTYLINE 25 MG. CHLORDIAZEPOXIDE I.P. 10 MG. EXCIPIENTS Q.S.
Amitriptyline is a tricyclic antidepressant (TCA). It is the most widely used TCA and has at least equal efficacy
against depression as the newer class of SSRIs. Amitriptyline acts primarily as a serotonin-norepinephrine reuptake inhibitor,
with strong actions on the serotonin transporter and moderate effects on the norepinephrine transporter.
Chlordiazepoxide Chlordiazepoxide is a sedative/hypnotic drug and benzodiazepine. Chlordiazepoxide has a very long
half-life. The drug has amnestic, anxiolytic, hypnotic, anticonvulsant and skeletal muscle relaxant properties. Chlordiazepoxide
acts on benzodiazepine subreceptors of the main GABAA receptor and this results in an increased binding of the inhibitory
neurotransmitter GABA to the GABAA receptor thereby producing inhibitory effects on the central nervous system and body similar
to the effects of other benzodiazepines.
INDICATIONS
Moderate to Severe Depression is a state of low mood to activity or apathy that can affect a person's thoughts,
behavior, feelings and sense of well-being. People with a depressed mood can feel sad, anxious, empty, hopeless, helpless,
worthless, guilty, irritable, angry, ashamed or restless. Insomnia, excessive sleeping, fatigue, aches, pains, digestive
problems or reduced energy may also be present.
Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behavior,
such as pacing back and forth, somatic complaints, and rumination. It is the subjectively unpleasant feelings of dread
over anticipated events. Anxiety is not the same as fear, which is a response to a real or perceived immediate threat,
whereas anxiety is the expectation of future threat.
Mood disorder is a group of diagnoses in the Diagnostic and Statistical Manual of Mental Disorders (DSM)
classification system where a disturbance in the person's mood is hypothesized to be the main underlying feature.
The classification is known as mood (affective) disorders in International Classification of Diseases (ICD).
NOTE
Concomitant drugs are two or more drugs used or given at or almost at the same time.
DOSE
One tablet once or twice daily or as directed by the doctor.
INTRODUCTION
AMITRIPTYLINE 10 mg & 25 mg respectively. AMITRIPTYLINE HYDROCHLORIDE I.P. EQV. TO AMITRIPTYLINE 12.5MG. CHLORDIAZEPOXIDE I.P. 5MG. EXCIPIENTS Q.S.
EACH FILM COATED CONTAINS: AMITRIPTYLINE HYDROCHLORIDE I.P. EQV. TO AMITRIPTYLINE 25 MG. CHLORDIAZEPOXIDE I.P. 10 MG. EXCIPIENTS Q.S.
Amitriptyline is a tricyclic antidepressant (TCA). It is the most widely used TCA and has at least equal efficacy against depression as the newer class of SSRIs. Amitriptyline acts primarily as a serotonin-norepinephrine reuptake inhibitor, with strong actions on the serotonin transporter and moderate effects on the norepinephrine transporter.
Chlordiazepoxide Chlordiazepoxide is a sedative/hypnotic drug and benzodiazepine. Chlordiazepoxide has a very long half-life. The drug has amnestic, anxiolytic, hypnotic, anticonvulsant and skeletal muscle relaxant properties. Chlordiazepoxide acts on benzodiazepine subreceptors of the main GABAA receptor and this results in an increased binding of the inhibitory neurotransmitter GABA to the GABAA receptor thereby producing inhibitory effects on the central nervous system and body similar to the effects of other benzodiazepines.
Moderate to Severe Depression is a state of low mood to activity or apathy that can affect a person's thoughts, behavior, feelings and sense of well-being. People with a depressed mood can feel sad, anxious, empty, hopeless, helpless, worthless, guilty, irritable, angry, ashamed or restless. Insomnia, excessive sleeping, fatigue, aches, pains, digestive problems or reduced energy may also be present.
Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behavior, such as pacing back and forth, somatic complaints, and rumination. It is the subjectively unpleasant feelings of dread over anticipated events. Anxiety is not the same as fear, which is a response to a real or perceived immediate threat, whereas anxiety is the expectation of future threat.
Mood disorder is a group of diagnoses in the Diagnostic and Statistical Manual of Mental Disorders (DSM) classification system where a disturbance in the person's mood is hypothesized to be the main underlying feature. The classification is known as mood (affective) disorders in International Classification of Diseases (ICD).
Concomitant drugs are two or more drugs used or given at or almost at the same time.
One tablet once or twice daily or as directed by the doctor.