Bacillus coagulans is a lactic acid-forming bacterial species. The organism is mixed with Lactobacillus and
Bacillus . Many bacteria and other organisms live in our bodies normally. "Friendly" bacteria such as lactobacillus
can help us break down food, absorb nutrients, and fight off "unfriendly" organisms that might cause diseases such
as diarrhea. Typical doses range from 1 to 10 billion living organisms taken daily in 3-4 divided doses. Alternative
Medicine Review recommends a daily dosage of 100 mg of Lactobacillus sporogenes, containing 1.5 billion colony-forming
units. MedlinePlus states that a dosage of 100 million live Lactobacillus sporogenes bacteria, taken daily for the
first year of life, has been used to prevent diarrhea in infants in developing countries, but also notes that not
enough research has been conducted to determine appropriate dosages of this probiotic.
A diastase is any one of a group of enzymes which catalyses the breakdown of starch into maltose. Diastase was
the first enzyme discovered.
Papain, also known as papaya proteinase I, is a enzyme present in papaya (Carica papaya) and mountain papaya
(Vasconcellea cundinamarcensis). Papain breaks down tough meat fibres, and has been used for thousands of years to
tenderise meat eaten in its native South America.
Simethicone Simethicone is an orally administered anti-foaming agent used to reduce bloating, discomfort or
pain caused by excessive gas — mainly swallowed air, with small amounts of hydrogen and methane— in the stomach or
intestines. Simethicone is a mixture of polydimethylsiloxane and hydrated silica gel. Simethicone is an anti-foaming
agent that decreases the surface tension of gas bubbles, causing them to combine into larger bubbles in the stomach
that can be passed more easily. Simethicone does not reduce or prevent the formation of gas in the digestive tract;
rather, it increases the rate at which it exits the body. Simethicone can relieve pain caused by gas in the intestines
by decreasing foaming, which then allows for easier passing of flatulence.
VitB12 is Cyanocobalamin requirement is 1 mcg and Deficiency causes ineffective haemopoiesis, Generalised
debility. It is a water soluble B vitamin. The mechanism of action is straightforward: the hydroxycobalamin hydroxide
ligand is displaced by the toxic cyanide ion, and the resulting harmless B12 complex is excreted in urine.B12 is also
known as cobalamin because it contains cobalt. B12 is only produced by bacteria. So it is only found in food products
of animal origin and in some fermented vegetable products. B12 works closely with another B vitamin, Folic acid in
reactions involved with DNA synthesis, blood cell formation, nervous sytem formation and heart health.
Lysine (abbreviated as Lys or K) is an α-amino acid that is used in the biosynthesis of proteins.
It contains an α-amino group, an α-carboxylic acid group, and a side chain lysyl classifying it as a charged (at
physiological pH) aliphatic amino acid. It is essential in humans, meaning the body cannot synthesize it and thus it
must be obtained from the diet. The nutritional requirement per day, in milligrams of lysine per kilogram of body
weight, is: infants (3–4 months) 103 mg/kg, children (2 years) 64 mg/kg, older children (10–12 years) 44 to 60 mg/kg,
adults 12 mg/kg. For a 70 kg adult, 12 milligrams of lysine per kilogram of body weight is 0.84 grams of lysine.
Recommendations for adults have been revised upwards to 30 mg/kg. Lysine is metabolised in mammals to give acetyl-CoA,
via an initial transamination with α-ketoglutarate.
VitB6 is Pyridoxin requirement is 1-2 mg and Deficiency causes Pellagra.
Nicotinamide(Niacinamide) or PPF requirement is 15-20 mg and Deficiency causes Pellagra(Dermatitis &
Pigmentation of skin).
Folic acid is essential for normal erythropoiesis process by exogenous administration. Folic acid is vital for
the biosynthesis of purines and thymidylate of nucleic acids. Folic acid is rapidly absorbed in the proximal portion
of the small intestine. After oral administration, the Cmax can be achieved within one hour. Folic acid is well-distributed
in all over the body tissues and stored in hepatic tissues. Folic acid is metabolized in liver into dihydrofolate and
tetrahydrofolate forms. About 90% of the administered dose is excreted via the urine. Daily requirement in general
is 0.2 mg.
INDICATIONS
Infantile Colic also known as Baby colic, is defined as episodes of crying for more than three hours a day, for
more than three days a week, for three weeks in an otherwise healthy child. Often crying occurs in the evening. The
crying can cause frustration for the parents, depression following delivery, excess visits to the doctor, and child abuse.
The cause of colic is unknown. Some believe it is due to gastrointestinal discomfort like intestinal cramping. Diagnosis
requires ruling out other possible causes. Colic affects 10–40% of children. It is most common at six weeks of age and
typically goes away by six months of age. It rarely lasts up to one year of age. It occurs at the same rate in boys and
in girls.
INTRODUCTION
Each 5 ml reconstituted suspension contains: LACTOBACILLUS SPPOROGENES 40X106 DIASTASE (1:800) I.P. 25MG. PAPAIN I.P. 20MG. SIMETHICONE I.P.40MG. VITAMIN B12 I.P. 1 MCG. L-LYSINE MONO HYDROCHLORIDE U.S.P. 5MG. VITAMIN B6 I.P. 0.5 MG. NIACINAMIDE I.P. 15 MG. FOLIC ACID I.P. 75 MCG.
Bacillus coagulans is a lactic acid-forming bacterial species. The organism is mixed with Lactobacillus and Bacillus . Many bacteria and other organisms live in our bodies normally. "Friendly" bacteria such as lactobacillus can help us break down food, absorb nutrients, and fight off "unfriendly" organisms that might cause diseases such as diarrhea. Typical doses range from 1 to 10 billion living organisms taken daily in 3-4 divided doses. Alternative Medicine Review recommends a daily dosage of 100 mg of Lactobacillus sporogenes, containing 1.5 billion colony-forming units. MedlinePlus states that a dosage of 100 million live Lactobacillus sporogenes bacteria, taken daily for the first year of life, has been used to prevent diarrhea in infants in developing countries, but also notes that not enough research has been conducted to determine appropriate dosages of this probiotic.
A diastase is any one of a group of enzymes which catalyses the breakdown of starch into maltose. Diastase was the first enzyme discovered.
Papain, also known as papaya proteinase I, is a enzyme present in papaya (Carica papaya) and mountain papaya (Vasconcellea cundinamarcensis). Papain breaks down tough meat fibres, and has been used for thousands of years to tenderise meat eaten in its native South America.
Simethicone Simethicone is an orally administered anti-foaming agent used to reduce bloating, discomfort or pain caused by excessive gas — mainly swallowed air, with small amounts of hydrogen and methane— in the stomach or intestines. Simethicone is a mixture of polydimethylsiloxane and hydrated silica gel. Simethicone is an anti-foaming agent that decreases the surface tension of gas bubbles, causing them to combine into larger bubbles in the stomach that can be passed more easily. Simethicone does not reduce or prevent the formation of gas in the digestive tract; rather, it increases the rate at which it exits the body. Simethicone can relieve pain caused by gas in the intestines by decreasing foaming, which then allows for easier passing of flatulence.
VitB12 is Cyanocobalamin requirement is 1 mcg and Deficiency causes ineffective haemopoiesis, Generalised debility. It is a water soluble B vitamin. The mechanism of action is straightforward: the hydroxycobalamin hydroxide ligand is displaced by the toxic cyanide ion, and the resulting harmless B12 complex is excreted in urine.B12 is also known as cobalamin because it contains cobalt. B12 is only produced by bacteria. So it is only found in food products of animal origin and in some fermented vegetable products. B12 works closely with another B vitamin, Folic acid in reactions involved with DNA synthesis, blood cell formation, nervous sytem formation and heart health.
Lysine (abbreviated as Lys or K) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group, an α-carboxylic acid group, and a side chain lysyl classifying it as a charged (at physiological pH) aliphatic amino acid. It is essential in humans, meaning the body cannot synthesize it and thus it must be obtained from the diet. The nutritional requirement per day, in milligrams of lysine per kilogram of body weight, is: infants (3–4 months) 103 mg/kg, children (2 years) 64 mg/kg, older children (10–12 years) 44 to 60 mg/kg, adults 12 mg/kg. For a 70 kg adult, 12 milligrams of lysine per kilogram of body weight is 0.84 grams of lysine. Recommendations for adults have been revised upwards to 30 mg/kg. Lysine is metabolised in mammals to give acetyl-CoA, via an initial transamination with α-ketoglutarate.
VitB6 is Pyridoxin requirement is 1-2 mg and Deficiency causes Pellagra.
Nicotinamide(Niacinamide) or PPF requirement is 15-20 mg and Deficiency causes Pellagra(Dermatitis & Pigmentation of skin).
Folic acid is essential for normal erythropoiesis process by exogenous administration. Folic acid is vital for the biosynthesis of purines and thymidylate of nucleic acids. Folic acid is rapidly absorbed in the proximal portion of the small intestine. After oral administration, the Cmax can be achieved within one hour. Folic acid is well-distributed in all over the body tissues and stored in hepatic tissues. Folic acid is metabolized in liver into dihydrofolate and tetrahydrofolate forms. About 90% of the administered dose is excreted via the urine. Daily requirement in general is 0.2 mg.
Infantile Colic also known as Baby colic, is defined as episodes of crying for more than three hours a day, for more than three days a week, for three weeks in an otherwise healthy child. Often crying occurs in the evening. The crying can cause frustration for the parents, depression following delivery, excess visits to the doctor, and child abuse. The cause of colic is unknown. Some believe it is due to gastrointestinal discomfort like intestinal cramping. Diagnosis requires ruling out other possible causes. Colic affects 10–40% of children. It is most common at six weeks of age and typically goes away by six months of age. It rarely lasts up to one year of age. It occurs at the same rate in boys and in girls.
Cytokines are important in cell signaling.
As per registered medical practitioners.